The case history of young women suffering from type 1 diabetes mellitus presents late diagnosis of abdominal aortae closure. The diagnosis was performed almost 20 years after problems were first announced. The patient is treated for type 1 diabetes from its 8 years. She was complaining about lower leg pain while running, walking from her 10 years. The special neurologic, revmatology examinations were collected. Diabetes was charged of presented painfulness. Patient consecutively got used to having such type of moving problems, no additional complaining. 25 years later regulary preventive angiology examination was performed with surprising result. Tight coarctation abdominal aortae was found just after renal vessels cession. Presented case shows the fact, that not only diabetes is the primary reason for every diabetic problem. Entire differential diagnostic discretion should be implemented.

Key words: diabetes mellitus type 1, lower leg pain, diabetic neuropathy, abdominal aortae coarctation

The paper presents the therapy of type 2 diabetes mellitus in a pregnant woman from Libya. We recommended the intensive insulin therapy along with dietary and lifestyle intervention. The goal of good glycemic control during pregnancy was achieved through frequent adjustments of therapy and patient education. The multi-cultural approach of the health care team contributed to good compliance of the patient, and to satisfactory metabolic control. The patient delivered a healthy newborn in the 37th week of pregnancy.

Key words: type 2 diabetes mellitus, pregnancy, intensive insulin therapy

Dyspepsia is more frequent in diabetic than in non-diabetic population. It results from several factors – dyskinesia of digestive system, altered visceral sensitivity, dysfunction of autonomous nervous system, alteration of intestinal absorption and secretion, effect of medication, micro- or macroangiopathy, altered levels of gastrointestinal hormones, and secondary bacterial overgrowth in the small intestine. The achievement of the best possible compensation of diabetes is essential for its treatment. Individual medication is chosen according to the most predominating type of complaint. Prokinetics are mainly used in the upper dyspepsia, antidiarrhoics in diarrhea; and laxatives, preferably contact or osmotic, are used in constipation. 

Key words: diabetes mellitus, dyspepsia, diarrhea, constipation

Isolated hypothyroxinemia in pregnancy is suspected to cause disorders of nervous system in infants. The aim of our retrospective survey was to assess the thyroidal functions in females with gestational diabetes who were followed up in our centre, and to figure out interannual trends. We have found out a higher frequency of isolated hypothyroxinemia than reported in the healthy pregnant population and we have suggested mutual relationship between hypothyroxinemia and the need of insulin in pregnancy. 

Key words: hypothyroxinemia, gestational diabetes mellitus, thyroid gland, pregnancy

Authors present a review of literary information and own experiences about bone development in osteopathy of prematurity. In a case report of originally extremely premature twins with multiple neonatal morbidity show densitometry use in children with osteopathy. During long-term calcium, phosphate and vitamine D supplementation the bone density normalized by 3 years in twin A and by 4 years in twin B. Results of own studies show, that it is useful to supplement bone minerals until the pre-school age in extremely premature children, when normal skeletal mineralisation is found in densitometry examination. 

Key words: osteopathy of prematurity, densitometry, bone minerals supplementation