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Schroner, Z., Staník, J., Gašperíková, D., Hučková, M., Škopková, M., Barák, Ľ., Michálek, J., Klimeš, I. DNA diagnostics allows to confirm clinical suspicion of MODY-3 type diabetes mellitus and to switch from therapy by insulin to sulphonylurea derivates treatment. Kazuistiky v diabetologii 4, č. 2: 4–9,
2006. |
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The case report discusses a case from a diabetology outpatients-in Moldava nad Bodvou, where a 24 years old man with MODY-3 diabetes mellitus was successfully switched from insulinotherapy to oral therapy by sulphonylurea tablets based on DNA
diagnostics.
Key words: DNA diagnostics, MODY-3, treatment modification, sulphonylurea derivates
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Šimek, S., Danzig, V., Šimková, R., Horák, J., Kuchynka, P., Linhart, A. Treatment of thrombotic occlusion of degenerated saphenous aortocoronary bypass graft. Kazuistiky v diabetologii 4, č. 2: 10–12,
2006. |
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Percutaneous coronary interventions on old heavy degenerated saphenous aortocoronary bypasses are often complicated with peripheral embolisations and ischaemic events. In some patients however PCI remains the only one possibility of treatment. We report the successful gradual approach to reopen the 13 years old bypass filed with excessive amount of thrombi in old patient with type 2
diabetes.
Key words: degenerated saphenous bypass, coronary intervention, bypass thrombosis
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Sosna, T., Pugner, K., Netuková, M. Ophthalmologist’s notes to evaluate hypertonic angiopathy, retinopathy and angiosclerosis.
Kazuistiky v diabetologii 4, č. 2: 14–19, 2006. |
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The description and interpretation of hypertonic and sclerotic changes in funduscopy is rather confusing. Authors discuss individual steps resulting in changes of retinal vessels. They characterize the scale of hypertonic changes and point out the options and limitations of interpreting the results of funduscopic
examination.
Key words: funduscopy, hypertonic changes, crossing phenomena |
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Doleželová, I., Klevetová, D. Hypertension in elderly. Case history.
Kazuistiky v diabetologii 4, č. 2: 20–24, 2006. |
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Titlbach, M., Maňáková, E. Previous and recent opinions on the pancreatic development and the development of diabetes mellitus.
Kazuistiky v diabetologii 4, č. 2: 25–28, 2006. |
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Key words: pancreas, diabetes mellitus, histology, embryology, comparative histology, immunohistochemistry, ultrastructural cytology, molekular biology
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Marunová, M. Congenital adrenal hyperplasia with partial 3-ß-hydroxysteroid dehydrogenase deficiency in adult male. Case history.
Kazuistiky v diabetologii 4, č. 2 – Endokrinologie: 34–40, 2006. |
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A case history of 23 years old male with congenital adrenal hyperplasia with partial
3-ß-hydroxysteroid dehydrogenase deficiency is documented. The case describes a rare type of congenital adrenal hyperplasia that can remain undiagnosed up to adulthood or it can persist for whole life without clinical manifestation. The evidence for diagnose is determined by elevation of the dehydroepiandrosterone and the 17-hydroxy-pregnenolone and parallel decrease of basal testosterone or decrease of testosterone following adrenocorticotropine stimulation. These patients do not necessarily have cortisol secretion
impairment.
Key words: 3-ß-hydroxysteroid dehydrogenase, gynecomastia,
hypogonadism, congenital adrenal hyperplasia
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